Anti-ALS2 (Mouse Monoclonal) Antibody from ABM, 100 µg Data Sheet Antibody Type: Primary Antibody  Accession #: NM_001135745.1 Description: This gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. Immunogen: Recombinant fragment: PSQDLKPVPE RCNQCSQLLI TMTDKEDHVI ISDSHCCPLG VTLTESQAEN HASTALSPST ETLDRQEEVF ENTLVANDQS VATELNAVSA QITSSDAMSS, corresponding to amino acids 221-321 of Human Als2. Species Reactivity: Mouse, not tested in other organisms. Tested Applications: WB Isotype: IgG1 kappa Purity: Affinity purified Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide Formlation: Liquid Concentration: 100 µg/100 µl Storage: This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Caution: Anti-ALS2 (Mouse Monoclonal) Antibody is for research use only and is not intended for therapeutic or diagnostic applications. Please contact your Territory Manager for more information.
$305.00
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