Anti-MCL1 Antibody from ABM, 100 µg Data Sheet Antibody Type: Antibody  Description: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]. Immunogen: Recombinant human MCL1 protein. Specificity: Recognize human MCL1 protein. Other species not tested. Tested Applications: WB and ELISA. Application Notes: Western blot (1:1000) and ELISA (1:2000~5000). Mcl-1 is an anti-apoptotic member of Bcl-2 family originally isolated from the ML-1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl-1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl-2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. Raised In: Mouse Clonality: MCL.C9 Isotype: IgG Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide Formulation: Liquid Concentration: 100 µg/100 µl Storage: This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Caution: Anti-MCL1 Antibody is for research use only and is not intended for therapeutic or diagnostic applications. Please contact your Territory Manager for more information.
$235.00
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