Anti-Myc Tag Antibody (Mouse Monoclonal) from ABM, 100 µg Data Sheet Antibody Type: Tag Antibody
Description: This gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini.
The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].
Immunogen: A synthetic peptide corresponding to residues 410-419 (EQKLISEEDL) coupled to KLH.
Specificity: Myc-tag Monoclonal Antibody. Recognises over-expressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins in transfected mammalian cells.
Tested Applications: CC/IF, ELISA, Dot Blot, WB, IP, ICC
Application Notes: Western Blot (1:1000), Immunoprecipitation and Immunostaining (1:200). Other dilutions will need optimization by end user.
Raised In: Mouse
Clonality: Myc.A7
Isotype: IgG1
Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide.
Formulation: Liquid
Concentration: 100 µg/100 µl
Storage: This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Caution: Anti-Myc Tag Antibody (Mouse Monoclonal) is for research use only and is not intended for therapeutic or diagnostic applications. Please contact your Territory Manager for more information.
