Anti-SCD1 (Mouse Monoclonal) Antibody from ABM, 100 µg  Data Sheet Antibody Type: Cholesterol Related Antibodies Immunogen: Full length recombinant protein. Specificity: Reacts with human and mouse proteins. Tested Applications: WB, ELISA, IP, and IHC
Application Notes: Western blot, ELISA, IP, and IHC in obesity research. Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa; ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders. Raised In: Mouse Clonality: CD.E10 Isotype: IgG Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide Formulation: Liquid Concentration: 100 µg/100 µl Storage: This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. Caution: Anti-SCD1 (Mouse Monoclonal) Antibody is for research use only and is not intended for therapeutic or diagnostic applications. Please contact your Territory Manager for more information.
$205.00
|
